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Influence of dose and exposition time in the effectiveness of N-Acetyl-l-cysteine treatment in A549 human epithelial cells

N-Acetyl-l-cysteine (NAC) acts as a precursor of the tripeptide glutathione (GSH), one of the principal cell mechanisms for reactive oxygen species (ROS) detoxification. Chronic obstructive pulmonary disease (COPD) is associated with enhanced inflammatory response and oxidative stress and NAC has be...

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Detalles Bibliográficos
Autores principales: Montero, Paula, Roger, Inés, Estornut, Cristina, Milara, Javier, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151372/
https://www.ncbi.nlm.nih.gov/pubmed/37144195
http://dx.doi.org/10.1016/j.heliyon.2023.e15613