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CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

Inflammatory responses are crucial for controlling infections and initiating tissue repair. However, excessive and uncontrolled inflammation causes inflammatory disease. Processing and release of the pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18 depend on caspase-1 activation within in...

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Detalles Bibliográficos
Autores principales: Devi, Savita, Indramohan, Mohanalaxmi, Jäger, Elisabeth, Carriere, Jessica, Chu, Lan H., de Almeida, Lucia, Greaves, David R., Stehlik, Christian, Dorfleutner, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151391/
https://www.ncbi.nlm.nih.gov/pubmed/36930645
http://dx.doi.org/10.1016/j.celrep.2023.112265