A targeted genetic modifier screen in Drosophila uncovers vulnerabilities in a genetically complex model of colon cancer

Received on 16 January 2023; accepted on 21 February 2023Kinases are key regulators of cellular signal transduction pathways. Many diseases, including cancer, are associated with global alterations in protein phosphorylation networks. As a result, kinases are frequent targets of drug discovery effor...

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Detalles Bibliográficos
Autores principales: Datta, Ishwaree, Vassel, Tajah, Linkous, Benjamin, Odum, Tyler, Drew, Christian, Taylor, Andrew, Bangi, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Mutant Screen Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151408/
https://www.ncbi.nlm.nih.gov/pubmed/36880303
http://dx.doi.org/10.1093/g3journal/jkad053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151408/
https://www.ncbi.nlm.nih.gov/pubmed/36880303
http://dx.doi.org/10.1093/g3journal/jkad053

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