Cargando…
A targeted genetic modifier screen in Drosophila uncovers vulnerabilities in a genetically complex model of colon cancer
Received on 16 January 2023; accepted on 21 February 2023Kinases are key regulators of cellular signal transduction pathways. Many diseases, including cancer, are associated with global alterations in protein phosphorylation networks. As a result, kinases are frequent targets of drug discovery effor...
Autores principales: | Datta, Ishwaree, Vassel, Tajah, Linkous, Benjamin, Odum, Tyler, Drew, Christian, Taylor, Andrew, Bangi, Erdem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151408/ https://www.ncbi.nlm.nih.gov/pubmed/36880303 http://dx.doi.org/10.1093/g3journal/jkad053 |
Ejemplares similares
-
Pharmaco-Genetic Screen To Uncover Actin Regulators Targeted by Prostaglandins During Drosophila Oogenesis
por: Spracklen, Andrew J., et al.
Publicado: (2019) -
A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis
por: Ables, Elizabeth T., et al.
Publicado: (2016) -
Uncovering Buffered Pleiotropy: A Genome-Scale Screen for mel-28 Genetic Interactors in Caenorhabditis elegans
por: Fernandez, Anita G., et al.
Publicado: (2013) -
A Genetic Screen in Drosophila To Identify Novel Regulation of Cell Growth by Phosphoinositide Signaling
por: Janardan, Vishnu, et al.
Publicado: (2019) -
A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease
por: Graves, Hillary K., et al.
Publicado: (2019)