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Advanced prodrug strategies in nucleoside analogues targeting the treatment of gastrointestinal malignancies

Gastrointestinal malignancies are common digestive system tumor worldwide. Nucleoside analogues have been widely used as anticancer drugs for the treatment of a variety of conditions, including gastrointestinal malignancies. However, low permeability, enzymatic deamination, inefficiently phosphoryla...

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Detalles Bibliográficos
Autores principales: Xu, Xingxing, Li, Zixuan, Yao, Xueying, Sun, Nannan, Chang, Junbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151537/
https://www.ncbi.nlm.nih.gov/pubmed/37143892
http://dx.doi.org/10.3389/fcell.2023.1173432