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Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

Prostate cancer (PC) is the most frequently diagnosed malignancy and a leading cause of cancer deaths in US men. Many PC cases metastasize and develop resistance to systemic hormonal therapy, a stage known as castration-resistant prostate cancer (CRPC). Therefore, there is an urgent need to develop...

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Detalles Bibliográficos
Autores principales: Zhang, Weijie, Lee, Adam M., Jena, Sampreeti, Huang, Yingbo, Ho, Yeung, Tietz, Kiel T., Miller, Conor R., Su, Mei-Chi, Mentzer, Joshua, Ling, Alexander L., Li, Yingming, Dehm, Scott M., Huang, R. Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151558/
https://www.ncbi.nlm.nih.gov/pubmed/37068243
http://dx.doi.org/10.1073/pnas.2218522120