Human airway and nasal organoids reveal escalating replicative fitness of SARS-CoV-2 emerging variants

The high transmissibility of SARS-CoV-2 Omicron subvariants was generally ascribed to immune escape. It remained unclear whether the emerging variants have gradually acquired replicative fitness in human respiratory epithelial cells. We sought to evaluate the replicative fitness of BA.5 and earlier...

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Detalles Bibliográficos
Autores principales: Li, Cun, Huang, Jingjing, Yu, Yifei, Wan, Zhixin, Chiu, Man Chun, Liu, Xiaojuan, Zhang, Shuxin, Cai, Jian-Piao, Chu, Hin, Li, Gang, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Yang, Zifeng, Jiang, Shibo, Yuen, Kwok-yung, Clevers, Hans, Zhou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151566/
https://www.ncbi.nlm.nih.gov/pubmed/37068258
http://dx.doi.org/10.1073/pnas.2300376120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151566/
https://www.ncbi.nlm.nih.gov/pubmed/37068258
http://dx.doi.org/10.1073/pnas.2300376120

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