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ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin

Protein translation, one of the most energy-consumptive processes in a eukaryotic cell, requires robust regulation, especially under energy-deprived conditions. A critical component of this regulation is the suppression of translational elongation through reduced ribosome association of the GTPase e...

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Detalles Bibliográficos
Autores principales: Piserchio, Andrea, Long, Kimberly J., Browning, Luke S., Bohanon, Amanda L., Isiorho, Eta A., Dalby, Kevin N., Ghose, Ranajeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151598/
https://www.ncbi.nlm.nih.gov/pubmed/37068230
http://dx.doi.org/10.1073/pnas.2300902120