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Complete variable domain sequences of monoclonal antibody light chains identified from untargeted RNA sequencing data

INTRODUCTION: Monoclonal antibody light chain proteins secreted by clonal plasma cells cause tissue damage due to amyloid deposition and other mechanisms. The unique protein sequence associated with each case contributes to the diversity of clinical features observed in patients. Extensive work has...

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Detalles Bibliográficos
Autores principales: Nau, Allison, Shen, Yun, Sanchorawala, Vaishali, Prokaeva, Tatiana, Morgan, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151772/
https://www.ncbi.nlm.nih.gov/pubmed/37143670
http://dx.doi.org/10.3389/fimmu.2023.1167235