Cargando…

Upregulation of Tribbles decreases body weight and increases sleep duration

Eukaryotic Tribbles proteins are pseudoenzymes that regulate multiple aspects of intracellular signalling. Both Drosophila melanogaster and mammalian members of this family of pseudokinases act as negative regulators of insulin signalling. Mammalian tribbles pseudokinase (TRIB) genes have also been...

Descripción completa

Detalles Bibliográficos
Autores principales: Popovic, Rebeka, Yu, Yizhou, Leal, Nuno Santos, Fedele, Giorgio, Loh, Samantha H. Y., Martins, L. Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151826/
https://www.ncbi.nlm.nih.gov/pubmed/37083954
http://dx.doi.org/10.1242/dmm.049942