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Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression

BACKGROUND: Chordoma is an extremely rare, locally aggressive malignant bone tumor originating from undifferentiated embryonic remnants. There are no effective therapeutic strategies for chordoma. Herein, we aimed to explore cellular interactions within the chordoma immune microenvironment and provi...

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Detalles Bibliográficos
Autores principales: Xu, Jiuhui, Shi, Qianyu, Lou, Jingbing, Wang, Boyang, Wang, Wei, Niu, Jianfang, Guo, Lei, Chen, Chenglong, Yu, Yiyang, Huang, Yi, Guo, Wei, Lan, Jianqiang, Zhu, Yu, Ren, Tingting, Tang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151997/
https://www.ncbi.nlm.nih.gov/pubmed/37185233
http://dx.doi.org/10.1136/jitc-2023-006808