Cargando…
Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression
BACKGROUND: Chordoma is an extremely rare, locally aggressive malignant bone tumor originating from undifferentiated embryonic remnants. There are no effective therapeutic strategies for chordoma. Herein, we aimed to explore cellular interactions within the chordoma immune microenvironment and provi...
Autores principales: | Xu, Jiuhui, Shi, Qianyu, Lou, Jingbing, Wang, Boyang, Wang, Wei, Niu, Jianfang, Guo, Lei, Chen, Chenglong, Yu, Yiyang, Huang, Yi, Guo, Wei, Lan, Jianqiang, Zhu, Yu, Ren, Tingting, Tang, Xiaodong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151997/ https://www.ncbi.nlm.nih.gov/pubmed/37185233 http://dx.doi.org/10.1136/jitc-2023-006808 |
Ejemplares similares
-
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis
por: Lou, Jingbing, et al.
Publicado: (2023) -
The role of tumor immune microenvironment in chordoma: promising immunotherapy strategies
por: Xu, Jiuhui, et al.
Publicado: (2023) -
miR-100-5p Inhibits Malignant Behavior of Chordoma Cells by Targeting IGF1R
por: Zhang, Hongliang, et al.
Publicado: (2020) -
Immune-Related LncRNAs Affect the Prognosis of Osteosarcoma, Which Are Related to the Tumor Immune Microenvironment
por: Huang, Qingshan, et al.
Publicado: (2021) -
Ccl3 enhances docetaxel chemosensitivity in breast cancer by triggering proinflammatory macrophage polarization
por: Sheng, Dandan, et al.
Publicado: (2022)