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Placental transcriptome analysis of hypertensive pregnancies identifies distinct gene expression profiles of preeclampsia superimposed on chronic hypertension

BACKGROUND: The pathogenesis of preeclampsia superimposed on chronic hypertension (SI) is poorly understood relative to preeclampsia (PreE) occurring in pregnant people without chronic hypertension. Placental transcriptomes in pregnancies complicated by PreE and SI have not been previously compared....

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Detalles Bibliográficos
Autores principales: Hesson, Ashley M., Langen, Elizabeth S., Plazyo, Olesya, Gudjonsson, Johann E., Ganesh, Santhi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152005/
https://www.ncbi.nlm.nih.gov/pubmed/37131171
http://dx.doi.org/10.1186/s12920-023-01522-x