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TFEB‐dependent lysosome biogenesis is required for senescence
The accumulation of senescent cells is recognised as a driver of tissue and organismal ageing. One of the gold‐standard hallmarks of a senescent cell is an increase in lysosomal content, as measured by senescence‐associated β‐galactosidase (Senβ‐Gal) activity. The lysosome plays a central role in in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152146/ https://www.ncbi.nlm.nih.gov/pubmed/36970883 http://dx.doi.org/10.15252/embj.2022111241 |