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Uptake‐independent killing of macrophages by extracellular Mycobacterium tuberculosis aggregates

Mycobacterium tuberculosis (Mtb) infection is initiated by inhalation of bacteria into lung alveoli, where they are phagocytosed by resident macrophages. Intracellular Mtb replication induces the death of the infected macrophages and the release of bacterial aggregates. Here, we show that these aggr...

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Detalles Bibliográficos
Autores principales: Toniolo, Chiara, Dhar, Neeraj, McKinney, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152147/
https://www.ncbi.nlm.nih.gov/pubmed/36920246
http://dx.doi.org/10.15252/embj.2023113490