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Plasmodium-encoded murine IL-6 impairs liver stage infection and elicits long-lasting sterilizing immunity

INTRODUCTION: Plasmodium sporozoites (SPZ) inoculated by Anopheles mosquitoes into the skin of the mammalian host migrate to the liver before infecting hepatocytes. Previous work demonstrated that early production of IL-6 in the liver is detrimental for the parasite growth, contributing to the acqui...

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Detalles Bibliográficos
Autores principales: Belhimeur, Selma, Briquet, Sylvie, Peronet, Roger, Pham, Jennifer, Commere, Pierre-Henri, Formaglio, Pauline, Amino, Rogerio, Scherf, Artur, Silvie, Olivier, Mecheri, Salaheddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152192/
https://www.ncbi.nlm.nih.gov/pubmed/37143657
http://dx.doi.org/10.3389/fimmu.2023.1143012