Cargando…

Plasmodium-encoded murine IL-6 impairs liver stage infection and elicits long-lasting sterilizing immunity

INTRODUCTION: Plasmodium sporozoites (SPZ) inoculated by Anopheles mosquitoes into the skin of the mammalian host migrate to the liver before infecting hepatocytes. Previous work demonstrated that early production of IL-6 in the liver is detrimental for the parasite growth, contributing to the acqui...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belhimeur, Selma, Briquet, Sylvie, Peronet, Roger, Pham, Jennifer, Commere, Pierre-Henri, Formaglio, Pauline, Amino, Rogerio, Scherf, Artur, Silvie, Olivier, Mecheri, Salaheddine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152192/ https://www.ncbi.nlm.nih.gov/pubmed/37143657 http://dx.doi.org/10.3389/fimmu.2023.1143012

Ejemplares similares

A genetically hmgb2 attenuated blood stage P. berghei induces crossed-long live protection
por: Briquet, Sylvie, et al.
Publicado: (2020)

Hepatic Inflammation Confers Protective Immunity Against Liver Stages of Malaria Parasite
por: Grand, Morgane, et al.
Publicado: (2020)

Protection against malaria in mice is induced by blood stage–arresting histamine-releasing factor (HRF)–deficient parasites
por: Demarta-Gatsi, Claudia, et al.
Publicado: (2016)

Looking for blood
por: Formaglio, Pauline, et al.
Publicado: (2015)

Strain-Transcendent Immune Response to Recombinant Var2CSA DBL5-ε Domain Block P. falciparum Adhesion to Placenta-Derived BeWo Cells under Flow Conditions
por: Fernandez, Pablo, et al.
Publicado: (2010)

Preparing for Transmission: Gene Regulation in Plasmodium Sporozoites
por: Briquet, Sylvie, et al.
Publicado: (2021)

DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites
por: Nardella, Flore, et al.
Publicado: (2019)

Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria
por: Porcherie, Adeline, et al.
Publicado: (2011)

MAEBL Contributes to Plasmodium Sporozoite Adhesiveness
por: Sá, Mónica, et al.
Publicado: (2022)

Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen
por: Jacob, Daria, et al.
Publicado: (2017)

Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite
por: Demarta-Gatsi, Claudia, et al.
Publicado: (2017)

Plasmodium sporozoites on the move: Switching from cell traversal to productive invasion of hepatocytes
por: Loubens, Manon, et al.
Publicado: (2020)

Humanized mice for investigating sustained Plasmodium vivax blood-stage infections and transmission
por: Luiza-Batista, Camilla, et al.
Publicado: (2022)

Plasmodium sporozoite disintegration during skin passage limits malaria parasite transmission
por: Kehrer, Jessica, et al.
Publicado: (2022)

The dimerisable Cre recombinase allows conditional genome editing in the mosquito stages of Plasmodium berghei
por: Fernandes, Priyanka, et al.
Publicado: (2020)

Plasmodium sporozoite search strategy to locate hotspots of blood vessel invasion
por: Formaglio, Pauline, et al.
Publicado: (2023)

Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease
por: Beghdadi, Walid, et al.
Publicado: (2008)

A toolbox for conditional control of gene expression in apicomplexan parasites
por: Briquet, Sylvie, et al.
Publicado: (2021)

Histamine H(3) Receptor-Mediated Signaling Protects Mice from Cerebral Malaria
por: Beghdadi, Walid, et al.
Publicado: (2009)

Duality and Complexity of Allergic Type Inflammatory Mechanisms in Determining the Outcome of Malaria Disease
por: Blank, Ulrich, et al.
Publicado: (2011)

The antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria
por: Roussilhon, Christian, et al.
Publicado: (2017)

Whole Pichia pastoris Yeast Expressing Measles Virus Nucleoprotein as a Production and Delivery System to Multimerize Plasmodium Antigens
por: Jacob, Daria, et al.
Publicado: (2014)

Role of host cell traversal by the malaria sporozoite during liver infection
por: Tavares, Joana, et al.
Publicado: (2013)

Recombinant measles vaccine expressing malaria antigens induces long-term memory and protection in mice
por: Mura, Marie, et al.
Publicado: (2019)

Plasmodium sporozoites require the protein B9 to invade hepatocytes
por: Fernandes, Priyanka, et al.
Publicado: (2023)

Theoretical Implications of a Pre-Erythrocytic Plasmodium vivax Vaccine for Preventing Relapses
por: White, Michael, et al.
Publicado: (2017)

Plasmodium P36 determines host cell receptor usage during sporozoite invasion
por: Manzoni, Giulia, et al.
Publicado: (2017)

The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts
por: Fernandes, Priyanka, et al.
Publicado: (2022)

Silence, activate, poise and switch! Mechanisms of antigenic variation in Plasmodium falciparum
por: Guizetti, Julien, et al.
Publicado: (2013)

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites
por: Chen, Patty B., et al.
Publicado: (2016)

A novel type of Plasmodium sporozoite transcellular migration
por: Rankin, Kathleen E, et al.
Publicado: (2010)

Asthma and atopic dermatitis are associated with increased risk of clinical Plasmodium falciparum malaria
por: Herrant, Magali, et al.
Publicado: (2013)

Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression
por: Vembar, Shruthi S, et al.
Publicado: (2014)

Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation
por: Briquet, Sylvie, et al.
Publicado: (2018)

TRSP is dispensable for the Plasmodium pre-erythrocytic phase
por: Costa, David Mendes, et al.
Publicado: (2018)

Single-cell RNA sequencing reveals developmental heterogeneity among Plasmodium berghei sporozoites
por: Ruberto, Anthony A., et al.
Publicado: (2021)

A rapid and robust selection procedure for generating drug-selectable marker-free recombinant malaria parasites
por: Manzoni, Giulia, et al.
Publicado: (2014)

Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems‐wide studies pave the way
por: Vembar, Shruthi Sridhar, et al.
Publicado: (2016)

Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas
por: Sasso, Maria Stella, et al.
Publicado: (2021)

Sterilization of the Unfit
por: Bogart, G. Henri
Publicado: (1912)

Cannot write session to /tmp/vufind_sessions/sess_m8j9o8p85fj24a49mbc0ku9bp7