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Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma

Beyond tertiary lymphoid structures, a significant number of immune-rich areas without germinal center-like structures are observed in non–small cell lung cancer. Here, we integrated transcriptomic data and digital pathology images to study the prognostic implications, spatial locations, and constit...

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Detalles Bibliográficos
Autores principales: Zhang, Hanyun, AbdulJabbar, Khalid, Moore, David A., Akarca, Ayse, Enfield, Katey S.S., Jamal-Hanjani, Mariam, Raza, Shan E. Ahmed, Veeriah, Selvaraju, Salgado, Roberto, McGranahan, Nicholas, Le Quesne, John, Swanton, Charles, Marafioti, Teresa, Yuan, Yinyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152235/
https://www.ncbi.nlm.nih.gov/pubmed/36853169
http://dx.doi.org/10.1158/0008-5472.CAN-22-2589