Cargando…
Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma
Beyond tertiary lymphoid structures, a significant number of immune-rich areas without germinal center-like structures are observed in non–small cell lung cancer. Here, we integrated transcriptomic data and digital pathology images to study the prognostic implications, spatial locations, and constit...
Autores principales: | Zhang, Hanyun, AbdulJabbar, Khalid, Moore, David A., Akarca, Ayse, Enfield, Katey S.S., Jamal-Hanjani, Mariam, Raza, Shan E. Ahmed, Veeriah, Selvaraju, Salgado, Roberto, McGranahan, Nicholas, Le Quesne, John, Swanton, Charles, Marafioti, Teresa, Yuan, Yinyin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152235/ https://www.ncbi.nlm.nih.gov/pubmed/36853169 http://dx.doi.org/10.1158/0008-5472.CAN-22-2589 |
Ejemplares similares
-
Self-supervised deep learning for highly efficient spatial immunophenotyping
por: Zhang, Hanyun, et al.
Publicado: (2023) -
Evolutionary characterisation of lung adenocarcinoma morphology in TRACERx
por: Karasaki, Takahiro, et al.
Publicado: (2023) -
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer
por: Wu, Yin, et al.
Publicado: (2022) -
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
por: McGranahan, Nicholas, et al.
Publicado: (2017) -
Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution
por: Thol, Kerstin, et al.
Publicado: (2022)