Reduced acetylated α-tubulin in SPAST hereditary spastic paraplegia patient PBMCs

HSP-SPAST is the most common form of hereditary spastic paraplegia (HSP), a neurodegenerative disease causing lower limb spasticity. Previous studies using HSP-SPAST patient-derived induced pluripotent stem cell cortical neurons have shown that patient neurons have reduced levels of acetylated α-tub...

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Detalles Bibliográficos
Autores principales: Wali, Gautam, Siow, Sue-Faye, Liyanage, Erandhi, Kumar, Kishore R., Mackay-Sim, Alan, Sue, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152469/
https://www.ncbi.nlm.nih.gov/pubmed/37144097
http://dx.doi.org/10.3389/fnins.2023.1073516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152469/
https://www.ncbi.nlm.nih.gov/pubmed/37144097
http://dx.doi.org/10.3389/fnins.2023.1073516

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