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Phenolic compounds as Nrf2 inhibitors: potential applications in cancer therapy

Cancer is a leading cause of death worldwide and involves an oxidative stress mechanism. The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative stress, including cancer growth and progression and therapy resistance. For this reason, inhibitors of Nrf2 are new t...

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Detalles Bibliográficos
Autores principales: Sharifi-Rad, Javad, Seidel, Veronique, Izabela, Michalak, Monserrat-Mequida, Margalida, Sureda, Antoni, Ormazabal, Valeska, Zuniga, Felipe A., Mangalpady, Shivaprasad Shetty, Pezzani, Raffaele, Ydyrys, Alibek, Tussupbekova, Gulmira, Martorell, Miquel, Calina, Daniela, Cho, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152593/
https://www.ncbi.nlm.nih.gov/pubmed/37127651
http://dx.doi.org/10.1186/s12964-023-01109-0