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Structural biology of DOCK‐family guanine nucleotide exchange factors
DOCK proteins are a family of multi‐domain guanine nucleotide exchange factors (GEFs) that activate the RHO GTPases CDC42 and RAC1, thereby regulating several RHO GTPase‐dependent cellular processes. DOCK proteins are characterized by the catalytic DHR2 domain (DOCK(DHR2)), and a phosphatidylinosito...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152721/ https://www.ncbi.nlm.nih.gov/pubmed/36271211 http://dx.doi.org/10.1002/1873-3468.14523 |