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Surface-anchored microbial enzyme-responsive solid lipid nanoparticles enabling colonic budesonide release for ulcerative colitis treatment

Colon-targeted oral drug delivery systems (CDDSs) are desirable for the treatment of ulcerative colitis (UC), which is a disease with high relapse and remission rates associated with immune system inflammation and dysregulation localized within the lining of the large bowel. However, the success of...

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Detalles Bibliográficos
Autores principales: Zhang, Yipeng, Wang, Liying, Wang, Zi-Dan, Zhou, Quan, Zhou, Xuefei, Zhou, Tianhua, Guan, Yi-Xin, Liu, Xiangrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152766/
https://www.ncbi.nlm.nih.gov/pubmed/37127609
http://dx.doi.org/10.1186/s12951-023-01889-0