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Expression of Enhancer of Zeste Homolog 2 (EZH2) Gene in Acute Myeloid Leukemia

BACKGROUND: Enhancer of Zeste Homolog 2 (EZH2) is the catalytic subunit of the chromatin modifying enzyme polycomb repressive complex 2 (PRC2). As a complex, these proteins selectively silence target genes through trimethylation of histone 3 at lysine 27. EZH2 is strongly oncogenic. It has been obse...

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Detalles Bibliográficos
Autores principales: Hamed, Nahla A. M., El Ghandour, Ashraf, Abo Elwafa, Reham A., Rezk, Mohamed Raafat, Gallab, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152850/
https://www.ncbi.nlm.nih.gov/pubmed/36708555
http://dx.doi.org/10.31557/APJCP.2023.24.1.81