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Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency

The interaction of T-cell receptors with peptide-major histocompatibility complex molecules (TCR-pMHC) plays a crucial role in adaptive immune responses. Currently there are various models aiming at predicting TCR-pMHC binding, while a standard dataset and procedure to compare the performance of the...

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Detalles Bibliográficos
Autores principales: Deng, Lihua, Ly, Cedric, Abdollahi, Sina, Zhao, Yu, Prinz, Immo, Bonn, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152969/
https://www.ncbi.nlm.nih.gov/pubmed/37143667
http://dx.doi.org/10.3389/fimmu.2023.1128326