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Metformin: update on mechanisms of action and repurposing potential

Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in most guidelines and is used daily by >200 million patients. Surprisingly, the mechanisms underlying its therapeutic action are complex and are still not fully understood. Early evidence highlighted the l...

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Detalles Bibliográficos
Autores principales: Foretz, Marc, Guigas, Bruno, Viollet, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153049/
https://www.ncbi.nlm.nih.gov/pubmed/37130947
http://dx.doi.org/10.1038/s41574-023-00833-4