Mining for a New Class of Fungal Natural Products: The Evolution, Diversity, and Distribution of Isocyanide Synthase Biosynthetic Gene Clusters

The products of non-canonical isocyanide synthase (ICS) biosynthetic gene clusters (BGCs) have notable bioactivities that mediate pathogenesis, microbial competition, and metal-homeostasis through metal-associated chemistry. We sought to enable research into this class of compounds by characterizing...

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Detalles Bibliográficos
Autores principales: Nickles, Grant R., Oestereicher, Brandon, Keller, Nancy P., Drott, Milton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153163/
https://www.ncbi.nlm.nih.gov/pubmed/37131656
http://dx.doi.org/10.1101/2023.04.17.537281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153163/
https://www.ncbi.nlm.nih.gov/pubmed/37131656
http://dx.doi.org/10.1101/2023.04.17.537281

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