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Increased activity of IRE1 improves the clinical presentation of EAE

Activation of the ER stress sensor IRE1α contributes to neuronal development and is known to induce neuronal remodeling in vitro and in vivo. On the other hand, excessive IRE1 activity is often detrimental and may contribute to neurodegeneration. To determine the consequences of increased activation...

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Detalles Bibliográficos
Autores principales: Bracchi-Ricard, Valerie, Nguyen, Kayla, Ricci, Daniela, Gaudette, Brian, Henao-Meija, Jorge, Brambilla, Roberta, Martynyuk, Tetyana, Gidalevitz, Tali, Allman, David, Bethea, John R., Argon, Yair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153167/
https://www.ncbi.nlm.nih.gov/pubmed/37131811
http://dx.doi.org/10.1101/2023.04.19.537391