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mRNA Localization and Local Translation of the Microtubule Severing Enzyme, Fidgetin-Like 2, in Polarization, Migration and Outgrowth

Cell motility requires strict spatiotemporal control of protein expression. During cell migration, mRNA localization and local translation in subcellular areas like the leading edge and protrusions are particularly advantageous for regulating the reorganization of the cytoskeleton. Fidgetin-Like 2 (...

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Detalles Bibliográficos
Autores principales: Birnbaum, Rayna, Biswas, Jeetayu, Singer, Robert H., Sharp, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153175/
https://www.ncbi.nlm.nih.gov/pubmed/37131812
http://dx.doi.org/10.1101/2023.04.17.537087