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D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response

Gene regulatory networks within cells modulate the expression of the genome in response to signals and changing environmental conditions. Reconstructions of gene regulatory networks can reveal the information processing and control principles used by cells to maintain homeostasis and execute cell-st...

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Detalles Bibliográficos
Autores principales: Jiang, Jialong, Chen, Sisi, Tsou, Tiffany, McGinnis, Christopher S., Khazaei, Tahmineh, Zhu, Qin, Park, Jong H., Strazhnik, Inna-Marie, Hanna, John, Chow, Eric D., Sivak, David A., Gartner, Zev J., Thomson, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153191/
https://www.ncbi.nlm.nih.gov/pubmed/37131803
http://dx.doi.org/10.1101/2023.04.19.537364