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D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response
Gene regulatory networks within cells modulate the expression of the genome in response to signals and changing environmental conditions. Reconstructions of gene regulatory networks can reveal the information processing and control principles used by cells to maintain homeostasis and execute cell-st...
Autores principales: | Jiang, Jialong, Chen, Sisi, Tsou, Tiffany, McGinnis, Christopher S., Khazaei, Tahmineh, Zhu, Qin, Park, Jong H., Strazhnik, Inna-Marie, Hanna, John, Chow, Eric D., Sivak, David A., Gartner, Zev J., Thomson, Matt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153191/ https://www.ncbi.nlm.nih.gov/pubmed/37131803 http://dx.doi.org/10.1101/2023.04.19.537364 |
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