Kinetic investigation reveals an HIV-1 Nef-dependent increase in AP-2 recruitment and productivity at endocytic sites

Lentiviruses express non-enzymatic accessory proteins whose function is to subvert cellular machinery in the infected host. The HIV-1 accessory protein Nef hijacks clathrin adaptors to degrade or mislocalize host proteins involved in antiviral defenses. Here, we investigate the interaction between N...

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Detalles Bibliográficos
Autores principales: Iwamoto, Yuichiro, Ye, Anna, Shirazinejad, Cyna, Hurley, James H., Drubin, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153213/
https://www.ncbi.nlm.nih.gov/pubmed/37131815
http://dx.doi.org/10.1101/2023.04.18.537262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153213/
https://www.ncbi.nlm.nih.gov/pubmed/37131815
http://dx.doi.org/10.1101/2023.04.18.537262

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