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High-resolution structure of a mercury cross-linked ZIP metal transporter reveals delicate motions and metal relay for regulated zinc transport

Zrt-/Irt-like protein (ZIP) divalent metal transporters play a central role in maintaining trace element homeostasis. The prototypical ZIP from Bordetella bronchiseptica (BbZIP) is an elevator-type transporter, but the dynamic motions and detailed transport mechanism remain to be elucidated. Here, w...

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Detalles Bibliográficos
Autores principales: Zhang, Tuo, Zhang, Yao, Sui, Dexin, Hu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153219/
https://www.ncbi.nlm.nih.gov/pubmed/37131590
http://dx.doi.org/10.1101/2023.04.20.537755