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Single-cell temporal dynamics reveals the relative contributions of transcription and degradation to cell-type specific gene expression in zebrafish embryos

During embryonic development, pluripotent cells assume specialized identities by adopting particular gene expression profiles. However, systematically dissecting the underlying regulation of mRNA transcription and degradation remains a challenge, especially within whole embryos with diverse cellular...

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Detalles Bibliográficos
Autores principales: Fishman, Lior, Nechooshtan, Gal, Erhard, Florian, Regev, Aviv, Farrell, Jeffrey A., Rabani, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153228/
https://www.ncbi.nlm.nih.gov/pubmed/37131717
http://dx.doi.org/10.1101/2023.04.20.537620