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A Computational Growth and Remodeling Framework for Adaptive and Maladaptive Pulmonary Arterial Hemodynamics

Hemodynamic loading is known to contribute to the development and progression of pulmonary arterial hypertension (PAH). This loading drives changes in mechanobiological stimuli that affect cellular phenotypes and lead to pulmonary vascular remodeling. Computational models have been used to simulate...

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Detalles Bibliográficos
Autores principales: Szafron, Jason M., Yang, Weiguang, Feinstein, Jeffrey A., Rabinovitch, Marlene, Marsden, Alison L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153237/
https://www.ncbi.nlm.nih.gov/pubmed/37131683
http://dx.doi.org/10.1101/2023.04.20.537714