Structure and assembly of a bacterial gasdermin pore

In response to pathogen infection, gasdermin (GSDM) proteins form membrane pores that induce a host cell death process called pyroptosis(1–33). Studies of human and mouse GSDM pores reveal the functions and architectures of 24–33 protomers assemblies(4–9), but the mechanism and evolutionary origin o...

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Detalles Bibliográficos
Autores principales: Johnson, Alex G., Mayer, Megan L., Schaefer, Stefan L., McNamara-Bordewick, Nora K., Hummer, Gerhard, Kranzusch, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153256/
https://www.ncbi.nlm.nih.gov/pubmed/37131678
http://dx.doi.org/10.1101/2023.04.20.537723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153256/
https://www.ncbi.nlm.nih.gov/pubmed/37131678
http://dx.doi.org/10.1101/2023.04.20.537723

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