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Structure and assembly of a bacterial gasdermin pore
In response to pathogen infection, gasdermin (GSDM) proteins form membrane pores that induce a host cell death process called pyroptosis(1–33). Studies of human and mouse GSDM pores reveal the functions and architectures of 24–33 protomers assemblies(4–9), but the mechanism and evolutionary origin o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153256/ https://www.ncbi.nlm.nih.gov/pubmed/37131678 http://dx.doi.org/10.1101/2023.04.20.537723 |