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Nuclear growth and import can be uncoupled

What drives nuclear growth? Studying nuclei assembled in Xenopus egg extract and focusing on importin α/β–mediated nuclear import, we show that, while nuclear growth depends on nuclear import, nuclear growth and import can be uncoupled. Nuclei containing fragmented DNA grew slowly despite exhibiting...

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Detalles Bibliográficos
Autores principales: Chen, Pan, Mishra, Sampada, Levy, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153267/
https://www.ncbi.nlm.nih.gov/pubmed/37131802
http://dx.doi.org/10.1101/2023.04.19.537556