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Suprabasal cells retaining stem cell identity programs drive basal cell hyperplasia in eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is an esophageal immune-mediated disease characterized by eosinophilic inflammation and epithelial remodeling, including basal cell hyperplasia (BCH) and loss of differentiation. Although BCH correlates with disease severity and with persistent symptoms in patients in...

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Detalles Bibliográficos
Autores principales: Clevenger, Margarette H., Karami, Adam L., Carlson, Dustin A., Kahrilas, Peter J., Gonsalves, Nirmala, Pandolfino, John E., Winter, Deborah R., Whelan, Kelly A., Tétreault, Marie-Pier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153277/
https://www.ncbi.nlm.nih.gov/pubmed/37131652
http://dx.doi.org/10.1101/2023.04.20.537495