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Suprabasal cells retaining stem cell identity programs drive basal cell hyperplasia in eosinophilic esophagitis
Eosinophilic esophagitis (EoE) is an esophageal immune-mediated disease characterized by eosinophilic inflammation and epithelial remodeling, including basal cell hyperplasia (BCH) and loss of differentiation. Although BCH correlates with disease severity and with persistent symptoms in patients in...
Autores principales: | Clevenger, Margarette H., Karami, Adam L., Carlson, Dustin A., Kahrilas, Peter J., Gonsalves, Nirmala, Pandolfino, John E., Winter, Deborah R., Whelan, Kelly A., Tétreault, Marie-Pier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153277/ https://www.ncbi.nlm.nih.gov/pubmed/37131652 http://dx.doi.org/10.1101/2023.04.20.537495 |
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