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Pannexin-1 channels promote CD8(+) T cell effector and memory responses through distinct intracellular pathways
Sensing of extracellular metabolites controls CD8(+) T cell function. Their accumulation can occur through export by specialized molecules, such as the release channel Pannexin-1 (Panx1). Whether Panx1 controls CD8(+) T cell immune responses to antigen, however, has not been previously addressed. He...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153284/ https://www.ncbi.nlm.nih.gov/pubmed/37131831 http://dx.doi.org/10.1101/2023.04.19.537580 |