Pannexin-1 channels promote CD8(+) T cell effector and memory responses through distinct intracellular pathways

Sensing of extracellular metabolites controls CD8(+) T cell function. Their accumulation can occur through export by specialized molecules, such as the release channel Pannexin-1 (Panx1). Whether Panx1 controls CD8(+) T cell immune responses to antigen, however, has not been previously addressed. He...

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Detalles Bibliográficos
Autores principales: Vardam-Kaur, Trupti, Banuelos, Alma, Gabaldon-Parish, Maria, Marie Wanhainen, Kelsey, Hanqi Zhou, Maggie, van Dijk, Sarah, Gois Macedo, Bruna, Loureiro Salgado, Caio, Santiago-Carvalho, Igor, Peng, Changwei, Jameson, Stephen C., Borges da Silva, Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153284/
https://www.ncbi.nlm.nih.gov/pubmed/37131831
http://dx.doi.org/10.1101/2023.04.19.537580

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