Cargando…

Genomic Analysis of Human Brain Metastases Treated with Stereotactic Radiosurgery Under the Phase-II Clinical Trial (NCT03398694) Reveals DNA Damage Repair at the Peripheral Tumor Edge

Stereotactic Radiosurgery (SRS) is one of the leading treatment modalities for oligo brain metastasis (BM), however no comprehensive genomic data assessing the effect of radiation on BM in humans exist. Leveraging a unique opportunity, as part of the clinical trial (NCT03398694), we collected post-S...

Descripción completa

Detalles Bibliográficos
Autores principales: Shireman, Jack M., White, Quinn, Agrawal, Namita, Ni, Zijian, Chen, Grace, Zhao, Lei, Gonugunta, Nikita, Wang, Xiaohu, Mccarthy, Liam, Kasulabada, Varshitha, Pattnaik, Akshita, Ahmed, Atique U., Miller, James, Kulwin, Charles, Cohen-Gadol, Aaron, Payner, Troy, Lin, Chih-Ta, Savage, Jesse J., Lane, Brandon, Shiue, Kevin, Kamer, Aaron, Shah, Mitesh, Iyer, Gopal, Watson, Gordon, Kendziorski, Christina, Dey, Mahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153341/
https://www.ncbi.nlm.nih.gov/pubmed/37131583
http://dx.doi.org/10.1101/2023.04.15.23288491