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Antiviral protection by antibodies targeting the glycan cap of Ebola virus glycoprotein requires activation of the complement system

Antibodies to Ebola virus glycoprotein (EBOV GP) represent an important correlate of the vaccine efficiency and infection survival. Both neutralization and some of the Fc-mediated effects are known to contribute the protection conferred by antibodies of various epitope specificities. At the same tim...

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Detalles Bibliográficos
Autores principales: Bukreyev, Alexander, Ilinykh, Philipp, Huang, Kai, Gunn, Bronwyn, Kuzmina, Natalia, Gilchuk, Pavlo, Alter, Galit, Crowe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153373/
https://www.ncbi.nlm.nih.gov/pubmed/37131834
http://dx.doi.org/10.21203/rs.3.rs-2765936/v1