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Pharmacophore Variants of the Macrocyclic Peptide Triazole Inactivator of HIV-1 Env
Previously we established a family of macrocyclic peptide triazoles (cPTs) that inactivate the Env protein complex of HIV-1, and identified the pharmacophore that engages Env’s receptor binding pocket. Here, we examined the hypothesis that the side chains of both components of the triazole Pro - Trp...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153383/ https://www.ncbi.nlm.nih.gov/pubmed/37131733 http://dx.doi.org/10.21203/rs.3.rs-2814722/v1 |