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A change in biophysical properties accompanies heterochromatin formation in mouse embryos

The majority of our genome is composed of repeated DNA sequences that assemble into heterochromatin, a highly compacted structure that constrains their mutational potential. How heterochromatin forms during development and how its structure is maintained are not fully understood. Here, we show that...

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Detalles Bibliográficos
Autores principales: Guthmann, Manuel, Qian, Chen, Gialdini, Irene, Nakatani, Tsunetoshi, Ettinger, Andreas, Schauer, Tamas, Kukhtevich, Igor, Schneider, Robert, Lamb, Don C., Burton, Adam, Torres-Padilla, Maria-Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153458/
https://www.ncbi.nlm.nih.gov/pubmed/37072228
http://dx.doi.org/10.1101/gad.350353.122