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A model for Scc2p stimulation of cohesin's ATPase and its inhibition by acetylation of Smc3p

The evolutionarily conserved cohesin complex mediates sister chromatid cohesion and facilitates mitotic chromosome condensation, DNA repair, and transcription regulation. These biological functions require cohesin's two ATPases, formed by the Smc1p and Smc3p subunits. Cohesin's ATPase acti...

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Detalles Bibliográficos
Autores principales: Boardman, Kevin, Xiang, Siheng, Chatterjee, Fiona, Mbonu, Udochi, Guacci, Vincent, Koshland, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153460/
https://www.ncbi.nlm.nih.gov/pubmed/37055084
http://dx.doi.org/10.1101/gad.350278.122