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Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia

Hypodiploid acute lymphoblastic leukemia (ALL) is an aggressive blood cancer with a poor prognosis despite intensive chemotherapy or stem cell transplant. Children and adolescents with positive end-of-induction minimal residual disease have an overall survival lower than 30%. However, data regarding...

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Detalles Bibliográficos
Autores principales: Pariury, Holly, Fandel, Joshua, Bachl, Stefanie, Ang, Kenny K., Markossian, Sarine, Wilson, Chris G., Braun, Benjamin S., Popescu, Bogdan, Wohlfeil, Margo, Beckman, Kyle, Xirenayi, Simayijiang, Roy, Ritu P., Olshen, Adam B., Smith, Catherine, Arkin, Michelle R., Loh, Mignon L., Diaz-Flores, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153511/
https://www.ncbi.nlm.nih.gov/pubmed/36700399
http://dx.doi.org/10.3324/haematol.2022.281443