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B- and T-cell acute lymphoblastic leukemias evade chemotherapy at distinct sites in the bone marrow

Persistence of residual disease after induction chemotherapy is a strong predictor of relapse in acute lymphoblastic leukemia (ALL). The bone marrow microenvironment may support escape from treatment. Using three-dimensional fluorescence imaging of ten primary ALL xenografts we identified sites of p...

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Detalles Bibliográficos
Autores principales: Barz, Malwine J., Behrmann, Lena, Capron, Danaëlle, Zuchtriegel, Gabriele, Steffen, Fabio D., Kunz, Leo, Zhang, Yang, Vermeerbergen, Iria Jimenez, Marovca, Blerim, Kirschmann, Moritz, Zech, Antonia, Nombela-Arrieta, César, Ziegler, Urs, Schroeder, Timm, Bornhauser, Beat, Bourquin, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153534/
https://www.ncbi.nlm.nih.gov/pubmed/36325888
http://dx.doi.org/10.3324/haematol.2021.280451