TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3’ neo-enhancer

T-cell acute lymphocytic leukemia protein 1 (TAL1) is one of the most frequently deregulated oncogenes in T-cell acute lymphoblastic leukemia (T-ALL). Its deregulation can occur through diverse cis-alterations, including SIL-TAL1 microdeletions, translocations with T-cell Receptor loci, and more rec...

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Detalles Bibliográficos
Autores principales: Smith, Charlotte, Goyal, Ashish, Weichenhan, Dieter, Allemand, Eric, Mayakonda, Anand, Toprak, Umut, Riedel, Anna, Balducci, Estelle, Manojkumar, Manisha, Pejkovska, Anastasija, Mücke, Oliver, Sollier, Etienne, Bakr, Ali, Breuer, Kersten, Lutsik, Pavlo, Hermine, Olivier, Spicuglia, Salvatore, Asnafi, Vahid, Plass, Christoph, Touzart, Aurore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Acute Lymphoblastic Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153542/
https://www.ncbi.nlm.nih.gov/pubmed/36632736
http://dx.doi.org/10.3324/haematol.2022.281583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153542/
https://www.ncbi.nlm.nih.gov/pubmed/36632736
http://dx.doi.org/10.3324/haematol.2022.281583

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